Recent Publications

If you are unable to access a copy of a publication, please contact Professor Michael Fagan

Journal papers

• LC Fitton, JF Shi, MJ Fagan, P O’Higgins. Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study. Accepted for publication in Journal of Anatomy.
• F Gröning, JA Bright, MJ Fagan, P O'Higgins. Improving the validation of finite element models with quantitative full-field strain comparisons. Journal of Biomechanics, Epub, 2012. LINK
• F Gröning, MJ Fagan. Comment on "The effects of modelling simplifications on craniofacial finite element models: The alveoli (tooth sockets) and periodontal ligaments" (volume 44, issue 10, pages 1831-1838). Journal of Biomechanics, Epub, 2012. LINK
• JA Khan, MNA Abdul Rahman, FAK Mazari, Y Shahin, G Smith, L Madden, MJ Fagan, J Greenman, PT McCollum, IC Chetter. Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms. Annals of Vascular Surgery, Epub, 2012. LINK
• R Hofe, SR Ell, MJ Fagan, JM Gilbert, PD GreenD, RK Moore, SI Rybchenko. Small-vocabulary speech recognition using a silent speech interface based on magnetic sensing. Speech Communication, Epub, 2012. LINK
• B Ji, R Patton, P Genever, D Putra, MJ Fagan. A novel mathematical model of bone remodelling cycles for trabecular bone at the cellular level. Biomechanics and Modeling in Mechanobiology. Online First, 2012. LINK 
• J Liu, JF Shi, LC Fitton, R Phillips, P O'Higgins, MJ Fagan. The application of muscle wrapping to voxel-based finite element models of skeletal structures. Biomechanics and Modeling in Mechanobiology, 11:1 35-47, 2012. LINK
• N Curtis, MEH Jones, P O’Higgins, SE Evans, MJ Fagan. Functional relationship between skull form and feeding mechanics in diapsid reptiles. PLoS One, 6:12, e29804, 2011. LINK
• MJ Higham, T Compton, C Stringer, R Jacobi, B Shapiro, E Trinkaus, B Chandler, F Gröning, C Collins, S Hillson, P O’Higgins, C FitzGerald, MJ Fagan. The earliest evidence for anatomically modern humans in Europe. Nature, 479, 521-524, 2011. LINK
• PG Cox, MJ Fagan, EJ Rayfield, N Jeffery. Biomechanical performance of the rodent skull: sensitivity analyses of finite element models of rat, guinea pig and squirrel skulls. Journal of Anatomy, 219, 696-709, 2011. LINK
• N Curtis, U Witzel, L Fitton, P O’Higgins, MJ Fagan. The mechanical significance of the temporal fasciae in Macaca fascicularis: an investigation using finite element analysis. Anatomical Record, 294:7, 1178-90, 2011. LINK
• MEH Jones, N Curtis, P O'Higgins, MJ Fagan, SE Evans. Hard tissue anatomy of the cranial joints in Sphenodon (Rhynchocephalia): sutures, kinesis, and skull mechanics. Accepted Palaeontologia Electronica, 14:2, 17A:92p, 2011. LINK
• F Gröning, J Liu, MJ Fagan, P O’Higgins. The effects of the periodontal ligament on mandibular stiffness: a study combining finite element analysis and geometric morphometrics. Journal of Biomechanics, 44:7, 1304-1312, 2011. LINK
• F Gröning, J Liu, MJ Fagan, P O’Higgins. Why do humans have chins? Testing the mechanical significance of modern human symphyseal morphology with finite element analysis. American Journal of Physical Anthropology, 144: 593-606, 2011. LINK
• P O’Higgins, S Cobb, LC Fitton, F Gröning, R Phillips, J Liu, M J Fagan. Combining geometric morphometrics and functional simulation: an emerging toolkit for virtual functional analyses. Journal of Anatomy, 218:1 3-15, 2011. LINK 
• N Curtis. Craniofacial biomechanics: an overview of recent multibody modelling studies. Journal of Anatomy, 218:1, 16-25, 2011. LINK
• PJ Watson, P O’Higgins, MJ Fagan, CA Dobson. Validation of a morphometric reconstruction technique, applied to a juvenile pelvis. Journal of Engineering in Medicine, 225:1, 48-57, 2011. LINK 
• N Curtis, MEH Jones, AK Lappin, P O’Higgins, SE Evans, MJ Fagan. Feedback control from the jaw joints during biting: an investigation of the reptile Sphenodon using multibody modelling. Journal of Biomechanics, 43:16, 3132-3137, 2010. LINK 
• O Panagiotopoulou, N Curtis, P O’Higgins, SN Cobb. Modelling subcortical bone in finite element analyses: a validation and sensitivity study in the macaque mandible. Journal of Biomechanics, 43, 1063-1611, 2010. LINK
• JM Gilbert, SI Rybchenko, R Hofe, SR Ell, MJ Fagan, RK Moore, P Green. Isolated word recognition of silent speech using magnetic implants and sensors. Engineering and Physics, 32, 1189-1197, 2010. LINK
• N Curtis, MEH Jones, AK Lappin, P O’Higgins, SE Evans, MJ Fagan. Comparison between in vivo and theoretical bite performance: using multi-body modelling to predict muscle and bite forces in a reptile skull. Journal of Biomechanics, 43:14, 2804-2809, 2010. LINK
• N Curtis, M Jones, SE Evans, P O'Higgins, MJ Fagan. Predicting muscle activation patterns from motion and anatomy: modelling the skull of Sphenodon (Diapsida: rhynchocephalia). Journal of the Royal Society Interface, 7, 153-160, 2010. LINK
• J McLeod, N Curtis, HD Lewis, MA Good, MJ Fagan, P Genever. Gamma-secretase-dependent cleavage of amyloid precursor protein regulates osteoblast behaviour. The FASEB Journal, 23:9, 2942-2955, 2009. LINK  
• N Curtis, M Jones, SE Evans, P O’Higgins, MJ Fagan. New methods for visualising muscle anatomy - describing the head and neck muscles of Sphenodon using three-dimensional computer models. Palaeontologia Electronica, 12:3, 7T:18pp, 2009.
• DJ Wilson, RL Morgan, KL Hesselden, JR Dodd, SW Janna, MJ Fagan. A single-channel telemetric intramedullary nail for in vivo measurement of fracture healing. Journal of Orthopaedic Trauma, 23:10, 702-709, 2009. LINK 
• M Jones, N Curtis, SE Evans, P O'Higgins, MJ Fagan. The head and neck muscles associated with feeding in Sphenodon (Reptilia: lepidosauria: rhynchocephalia). Palaeontologia Electronica, 12:2, 7A:56pp, 2009. LINK
• F Gröning, J Liu, MJ Fagan, P O'Higgins. Validating a voxel-based finite element model of a human mandible using digital speckle pattern interferometry. Accepted for publication in Journal of Biomechanics. 42, 1224-1229, 2009. LINK
• K Kupczik, CA Dobson, RH Crompton, R Phillips, CE Oxnard, MJ Fagan, P O'Higgins. Masticatory loading and bone adaptation in the supraorbital torus of developing macaques. Accepted for publication in American Journal of Physical Anthropology, 139: 193-203, 2009. LINK
• M Moazen, N Curtis, S E Evans, P O'Higgins, M J Fagan. Biomechanical assessment of evolutionary changes in the lepidosaurian skull. Proc Natl Acad Sci USA, 20, 8273-8277, 2009. LINK
• M Moazen, N Curtis, P O’Higgins, MEH Jones, SE Evans, MJ Fagan Assessment of the role of sutures in a lizard skull - a computer modelling study. Proceedings of the Royal Society, Part B, 276, 39-46, 2009. LINK
• M Moazen, N Curtis, SE Evans, P O’Higgins, MJ Fagan. Combined finite element and multibody dynamics analysis of biting in a Uromastyx hardwickii lizard skull. Journal of Anatomy, 213, 499-508, 2008.LINK
• RC Griffin, H Moody, KEH Penkman, MJ Fagan, N Curtis, MJ Collins. A new approach to amino acid racemization in enamel: testing of a less destructive sampling methodology. Journal of Forensic Sciences, 53:4, 910-916, 2008. LINK
• M Moazen, N Curtis, S Evans, P O’Higgins, MJ Fagan. Rigid body analysis of the lizard skull: modelling the skull of Uromastyx hardwickii. Journal of Biomechanics, 41:6, 1274-1280, 2008. LINK
• MJ Fagan, SR Ell, JM Gilbert, E Sarrazin, PM Chapman. Development of a (silent) speech recognition system for patients following laryngectomy. Medical Engineering and Physics, 30:4, 419-425, 2008. LINK
• N Curtis, K Kupczik, P O'Higgins, M Moazen, MJ Fagan. Predicting skull loading: applying multibody dynamics analysis to a macaque skull. The Anatomical Record, 291, 491-501, 2008. LINK
• K Mazik, N Curtis, MJ Fagan, S Taft, M Elliott. Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography. Journal of Experimental Marine Biology and Ecology, 354, 192-201, 2008. LINK
• MST Heng, MJ Fagan, JW Collier, G Desai, PT McCollum, IC Chetter. Peak wall stress measurement in elective and acute abdominal aortic aneurysms. Journal of Vascular Surgery, 47:1, 17-22, 2008. LINK
• K Kupczik, CA. Dobson, MJ Fagan, RH Crompton, CE Oxnard, P O'Higgins. Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models. Journal of Anatomy, 210:1, 41-53, 2007. LINK
• CA Dobson, G Sisias, CM Langton, R Phillips, MJ Fagan. Three dimensional stereolithography models of cancellous bone structures from microCT data: testing and validation of finite element results. Journal of Engineering in Medicine, 220:3, 481-484, 2006. LINK
• K Attenborough, Q Qin, MJ Fagan, H-C Shin, CM Langton. Measurements of tortuosity in stereolithographical bone replicas using audio-frequency pulses. Journal of the Acoustical Society of America, 118:5, 2779-2782, 2005. LINK
• AK Venkatasubramaniam, T Mehta, MJ Fagan, KJ Mylankal, G Kuhan, B Ray, IC Chetter, PT McCollum. A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysm. European Journal of Vascular and Endovascular Surgery , 28:2, 168-176, 2004. LINK
• WL Lam, A Garrido, J Vandermeulen, MJ Fagan, PRW Stanley. Cutting or round bodied needles for tendon repair. The Journal of Hand Surgery, 28B:5, 475-477, 2003. LINK
• R Phillips, JA Grunchec, JW Ward, MJ Fagan, CA Dobson, CM Langton, G Sisias. Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation. Studies in Health Technology Informatics, 94, 258-64, 2003.
• MJ Fagan, G Gie, G Heyse-Moore, AJC Lee, RSM Ling and AJ Timperley. The Exeter cementing technique for the femur. Surgical Techniques in Orthopaedics and Traumatology, 55-430-D-20, pp1-7, 2002.
• MJ Fagan, S Julian and A Mohsen. Finite element analysis in spine research. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 216, 281-298, 2002.
• MJ Fagan, S Julian, DJ Siddall, A Mohsen. Patient specific spine models - Part I: finite element analysis of the lumbar intervertebral disc - a material sensitivity study. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 216, 299-314, 2002.
• G Sisias, R Phillips, CA Dobson, MJ Fagan and CM Langton. Tessellation and contour extraction algorithms for accurate rapid prototyping replication of cancellous bone voxel maps. Rapid Prototyping Journal 8:1, 6-24, 2002.
• CA Dobson, G Sisias, CM Langton, R Phillips and MJ Fagan. The smoothing of pixelated finite element models of cancellous bone structures and the effects on the bone's predicted structural properties. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 216, 145-149, 2002.
• MJ Fagan, P Gillespie, S Julian, D Siddall, AMMA Mohsen. Development of an artificial intervertebral disc for a laboratory test spine. Journal of Biomechanics 34:S1, 58-59, 2001.
• MJ Fagan, P Gillespie, S Julian, D Siddall, AMMA Mohsen. Finite element analysis of the lumbar intervertebral disc - a material sensitivity study. Journal of Biomechanics 34:S1, 59-60, 2001.
• MJ Fagan and J McConnachie. A review and detailed examination of non-layered conformal contact by finite element analysis. Journal of Strain Analysis for Engineering Design, 36:2, 177-195, 2001.
• CM Langton, P S Ganney, CA Dobson, MJ Fagan, G Sisias and R Phillips. Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption. Bone, 27:1, 111-118, 2000.
• CA Dobson, CM Langton and MJ Fagan. Simulation of cancellous bone remodelling, structure and biomechanical stresses associated with osteoporosis: A review. Computer Simulation and Modelling in Medicine, 1:2, 79-97, 2000.
• MJ Fagan, S J Park and L Wang. Finite element analysis of the contact stresses in diamond coatings subjected to a uniform normal load. Diamond and Related Materials, 9:1, 26-36, 2000.
• CM Langton, CA Dobson, G Sisias, P S Ganney, R Phillips and MJ Fagan. Stochastic simulation of cancellous bone remodelling. Computer Simulation and Modelling in Medicine, 1:1, 22-27, 2000.
• MJ Fagan, CA Dobson, P S Ganney, G Sisias, R Phillips and CM Langton. Finite element analysis of cancellous bone resorption. Computer Methods in Biomechanics and Biomedical Engineering, 2:4, 257-270, 1999.
• CM Langton, T J Haire, CA Dobson and MJ Fagan. A dynamic stochastic simulation of cancellous bone resorption. Bone, 22:4, 375-380, 1998.
  

Abstracts in journals

• Ji B, Putra D, Patton R, Genever P, Fagan MJ. A predator-prey mathematical model of bone remodelling cycles at the cellular level. Osteoporosis International 21:S3, S517, 2010.
• Jahani M, Ahwal F, Ji B, Patton R, Genever P, Fagan MJ. Simulation of osteocyte apoptosis on signalling in the osteocyte-bone lining cell network and implications for osteoporosis. Osteoporosis International 21:S3, S514, 2010.
• Curtis N, Jones MEH, Evans SE, O’Higgins, Fagan MJ. The role and function for cranial sutures in reptiles: a finite element analysis of the skull of Sphenodon (Diapsida: Lepidosauria: Rhynchocephalia). Journal of Vertebrate Paleontology S30: 77A, 2010.
• Jones MEH, Curtis N, Evans SE, O’Higgins, Fagan MJ. Cranial joints in Sphenodon (Rhynchocephalia) and its fossil relatives with implications for lepidosaur skull mechanics. Journal of Vertebrate Paleontology S30: 113A, 2010.
• Putra D, Bingbing J, Patton R, Genever P, Fagan MJ. Simulation of the BMU remodelling cycle using a new predator-prey algorithm. Bone 47:1,S95, 2010.
• Jahani M, Ahwal F, Patton R, Genever P, Fagan MJ. The effect of osteocyte apoptosis on the signalling in the osteocyte network and at the bone lining cell surface: a computer simulation. Bone 47:1, S145-146, 2010.
• Fitton LC, Shi J, Liu J, Fagan MJ, O’Higgins P. Functional loading, facial remodelling and the formation of the maxillary sinus and maxillary fossa in Macaca fascicularis and Cercocebus torquatus. American Journal of Physical Anthropology 141:S50, 105, 2010.
•  Milne N, Fitton L, O’Higgins P, Kupczik K, Fagan MJ. The role of the zygomaticomaxillary suture in modulating strain distribution within the skull of Macaca fascicularis. HOMO - Journal of Comparative Human Biology 60:3, 281, 2009.
• O'Higgins P , Cobb SN, Fitton L, Groening F, Phillips R, Fagan MJ. Facial mechanics in early hominins: a study combining geometric morphometrics and finite elements analysis. American Journal of Physical Anthropology 138:S48, 2009.
• Gröning F, Fagan MJ, O'Higgins P. Mind the gap. A finite element study of the retromolar space and its relation to cortical thickness distribution in the mandibular ramus. American Journal of Physical Anthropology 138:S48, 2009.
• Fitton L, Kupczik K, Milne N, Fagan MJ, O'Higgins P. The role of sutures in modulating strain distribution within the skull of Macaca fascicularis. American Journal of Physical Anthropology 138:S48, 2009.
• Smith AL, Kupzik K, Fagan MJ, Rook L, Strait DS, Grosse IR, O'Higgins P. Changing faces: an examination of robust craniofacial features in Macaca majori and implications for the hominid fossil record. American Journal of Physical Anthropology 138:S48, 2009.
• Shi JF. Curtis N, Fitton L, O'Higgins P, Fagan MJ. The effect of variations in muscle positions in a complex biomechanical model of a macaque skull. American Journal of Physical Anthropology 138:S48, 2009.
• Putra D, Patton RJ, Genever PG, Fagan MJ. Mathematical model of remodelling cycles with feedback mechanism for maintaining the balance between bone resorption and formation. Journal of Bone and Mineral Research, 23, S509, 2008.
• N Curtis, SE Evans, M Jones, JF Shi, MJ Fagan Predicting muscle forces and activation rates during mastication; a multi-body computer modelling study of Sphenodon Punctatus (lepidosauria: rhynchocephalia). Journal of Vertebrate Palaeontology 28:S3, 71A, 2008.
• Shi J, Curtis N, Fitton L, O’Higgins P, Fagan MJ. Musculoskeletal modelling of a macaque skull – sensitivity studies. Journal of Vertebrate Palaeontology 28:S3, 141A, 2008.
• Smith A, Kupczik K, Fagan MJ, Rook, L, O’Higgins P. Geometric morphometrics and functional morphology of a Sardinian fossil macaque: warping and finite elements analysis of craniofacial features in Macaca majori. Journal of Vertebrate Palaeontology 28:S3, 143A, 2008.
• M Moazen, N Curtis, SE Evans, MEH Jones, MJ Fagan. The role of cranial sutures in a lizard skull: a finite element analysis investigation. Journal of Vertebrate Palaeontology 28:S3, ???, 2008.
• MNA Abdulrahman, MJ Fagan, J Greenman, PT McCollum, IC Chetter. Concentration and activity of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the wall of abdominal aortic aneurysm at different wall stress. Interactive Cardiovascular and Thoracic Surgery, 7:S1, S63, 2008.
• K Kornelius, CA Dobson, MJ Fagan, RH Crompton, CE Oxnard, P O'Higgins. Bone remodelling response to mechanical strains in the developing primate craniofacial skeleton. Journal of Morphology, 268:12, 1096, 2007.
• N Curtis, K Kupczik, MJ Fagan, SE Evans. Finite element modelling of the cat skull. Journal of Morphology, 268:12, 1063, 2007.
• MJ Fagan, N Curtis, CA Dobson, JH Karunanayake, K Kupczik, M Moazen, L Page, R Phillips, P O'Higgins. Voxel-based finite element analysis - working directly with microCT scan data. Journal of Morphology, 268:12, 1071, 2007.
• M Moazen, N Curtis, P O'Higgins, SE Evans, MJ Fagan. Musculoskeletal modelling and finite element analysis of lizard skulls. Journal of Morphology, 268:12, 1108, 2007.
• N Curtis, K Kupczik, P O'Higgins, MJ Fagan. Multibody dynamics analysis of a macaque skull. Journal of Morphology, 268:12, 1063, 2007.
• P O'Higgins, K Kupczik, CA Dobson, MJ Fagan, RH Crompton, CE Oxnard. Modelling the mechanical modulation of bone remodelling fields in the cercopithecine face. Journal of Anatomy, 210, 767-777, 2007.
• Kupczik K, Dobson CA, O'Higgins P, Fagan MJ, Crompton RH, Oxnard CE. Relating strain to craniofacial morphology in Macaca fascicularis: modelling and validation. Annals of Human Biology 32, 791, 2006.
• P O'Higgins, MJ Fagan, RH Crompton, K Kupczik, CA Dobson, CE Oxnard. Building the primate face: the ontogeny of mechanical adaptation in Macaca fascicularis. Journal of Anatomy, 206, 505, 2006.
• MST Heng, AK Venkatasubramaniam, MJ Fagan, JW Collier, GM Desai, B Ray, D Lee, I Chetter, PT McCollum. Peak wall stress; value and location in ruptured and non-ruptured AAAs. British Journal of Surgery 92:S1, 82, 2005.
• AK Venkatasubramaniam, MJ Fagan, I Chetter, PT McCollum. AAA geometry and systolic blood pressure are the principle determinants of risk of rupture. Journal of Vascular Biology, Medicine and Surgery, 109:S1, 2004.
• CM Langton, JA Thorpe, DK Langton, MJ Fagan. Experimental validation of finite element analysis of X-ray images for the prediction of osteoporotic fractures. Osteoporosis International, 15: 20, 2004 .
• AK Venkatasubramaniam, MJ Fagan, I Chetter, G Kuhan, T Mehta, K Mylankal, B Ray, PT McCollum. Abdominal aortic aneurysm (AAA) geometry and systemic blood pressure are the principle determinants of rupture risk in AAA. British Journal of Surgery 91:9, 1216, 2004.
• CA Dobson, G Sisias, R Phillips, CM Langton, MJ Fagan. The effect of periodical strain adaptation on the stochastic remodelling of cancellous bone structures: an anabolic simulation study. Calcified Tissue International, 72:4, 401, 2003.
• R Phillips, J-A Grunchec, JW Ward, MJ Fagan, CA Dobson, C Langton, G Sisias. The use of stereo visualization in a BMU-based simulator for bone remodelling. Calcified Tissue International, 72:4, 353, 2003.
• CA Dobson, G Sisias, E K Ong, B. Jones, R Phillips, CM Langton, MJ Fagan. 3D stereolithography models of cancellous bone structures from ï­CT data: Production, testing and validation of finite element results. Calcified Tissue International, 72:4, 401, 2003.
• A Venkatasubramaniam, MJ Fagan, T Mehta, K Mylankal, B Ray, G Kuhan, I Chetter, P McCollum. A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms. Irish Journal of Medical Science, 172:3 (S2), 29, 2003.
• D Siddall, P Gillespie, A Mohsen, MJ Fagan. Patient-specific spine models - development of a laboratory test spine for model validation. Journal of Bone and Joint Surgery, Suppl 2, November 2002.
• CA Dobson, G Sisias, R Phillips, MJ Fagan, CM Langton. The effect of strain adaptation on the anabolic remodelling of depleted cancellous bone structures. Acta Orthop. Scand. 73, 43, 2002.
• CA Dobson, G Sisias, R Phillips, MJ Fagan and CM Langton. Use of stereolithography models as a validation tool for FEA of cancellous bone structures. Acta Orthop. Scand. 73, 43, 2002.
• E K Ong, CA Dobson, G Sisias, R Phillips, MJ Fagan, CM Langton. Validation of the remodelling parameters used for the simulation of cancellous bone resorption. Acta Orthop. Scand. 73, 42, 2002.
• G Sisias, R Phillips, CA Dobson, MJ Fagan, CM Langton. Histomorphometry analysis - a novel application to simulation of strain-adaptation in cancellous bone. Acta Orthop. Scand. 73, 44, 2002.
• CA Dobson, G Sisias, CM Langton, R Phillips and MJ Fagan. Adaptive strain remodelling in a stochastic simulation of cancellous bone resorption. Osteoporosis International, 11:1, 61, 2000.