Pre-operative Optimisation of Diabetic Patients Prior to Major Lower Limb Surgery

About this project

Diabetes is a national and international epidemic. In the UK a new person is diagnosed every 2 minutes and care of diabetes costs the NHS £1million per hour, every hour. Peripheral arterial disease (PAD) affects 1 in 3 people with diabetes over 50 years of age and the incidence of limb loss is 15 times higher in diabetics. These patients also suffer excessive mortality related to surgical interventions with up to 70% dying within 5 years of surgery. Outcomes for these patients locally are some of the worst in the UK.

To help address this problem he University of Hull is offering the following PhD projects which together will form a cohort of students bridging the gap between basic sciences and clinical applications and trials in this important disease. Projects include collaborations between some of the strongest and most active basic science and clinical research departments within the university.

Pre-operative optimisation of diabetic patients prior to major lower limb surgery

Diabetes leads to complex interplay of dysfunction in multiple physiological systems which lead diabetic patient to suffer an excessive morbidity and mortality with major surgical intervention. This project will investigate how this high risk group might benefit from a preoperative pathway to assess cardiac, respiratory and renal function, anaemia, nutritional status and diabetic control with targeted interventions for optimisation prior to surgery. Patients will also receive counselling for conditioning of expectations during and after surgical admission. The project will aim to develop and test the impact of such a pathway with regards feasibility of introduction, acceptability to patients, clinical impact on patient outcomes and health economic potential.


You are strongly advised to contact a potential supervisor and to discuss your research proposal, well before you submit an application. Please refer to the Health research pages.

If you have any queries, please email Mr George Smith or Mr Dan Carradice.

Next steps


To celebrate the University's research successes, the University of Hull is offering a full-time UK/EU PhD Scholarship or International Fees Bursary.

Entry requirements

Applicants should have at least a 2.1 undergraduate degree in a related discipline, together with relevant research experience. It is anticipated that the successful applicant will have a 1st class undergraduate degree or Masters level qualification.

Medically qualified applicants in relevant specialties will have the opportunity to undertake clinical sessions and on call duties, with appropriate remuneration, alongside their research. 

How to apply

Applications for scholarship consideration at the University of Hull should be made through the Hull York Medical School postgraduate application system.

Please select PhD in Medical Sciences with a start date of “2018 October, full time” and quote the specific project title you wish to apply for. 

Applicants are strongly encouraged to first identify and contact a potential supervisor.

Apply now

Application deadline: Monday 26 March


Full-time UK/EU PhD Scholarships will include fees at the ‘home/EU' student rate and maintenance (£14,553 in 2017/18) for three years, depending on satisfactory progress.

Full-time International Fee PhD Studentships will include full fees at the International student rate for three years, dependent on satisfactory progress.